5/1/12

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"I have also heard rumor (from reliable sources) of a device under development by the Chinese government in Beijing, in collaboration with some Western scientists, going by the name of the "head brain instrument" (three Chinese characters). This device uses transcranial magnetic stimulation, and has the dual effects of increasing learning rate, and also increasing susceptibility to suggestion. Interesting. I read an article a few months ago about a different but related device being tested in Australia, using transcranial stimulation to increase creativity. This sort of research seems fascinating and promising. No doubt one could advance even faster and further in this direction using direct brain-computer interfacing, but no one has yet developed an inexpensive and safe method of installing a Neuromancer-style "cranial jack" in the brain, alas. I'm sure the cranial jack is coming, but it's hard to estimate exactly when.

In terms of ongoing and future research, I think that a combination of genomics, experimental evolution and artificial intelligence is fairly shortly going to lead us to a variety of therapies to improve cognitive performance throughout the human lifespan, as well as to extend the healthy human lifespan overall. I'm seeing this now in the work my bioinformatics firm Biomind is doing in collaboration with the biopharma firm Genescient Corp. Genescient has created a set of populations of long-lived fruit flies, which live over 4x as long as control flies, and also display enhanced cognitive capability throughout their lives, including late life. We've gathered gene expression and SNP data from these "superflies" and are using AI technology to analyze the data -- and the results are pretty exciting so far! We've discovered a large number of gene-combinations that are extremely strongly associated with both longevity and neural function, and many of these correspond to likely-looking life-extension and cognitive-enhancement pathways in the human organism. The supplement Stem Cell 100, now on the market, was inspired by this research; but that's just the start ... I think we're going to see a lot of new therapies emerge from this sort of research, including nutraceuticals, pharmaceuticals, gene therapy, and others."

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